Tan Chunyan

Aug. 2004，Ph.D. in Organic Chemistry 

Department of Chemistry, University of Florida, Gainesville, FL, USA

July. 1998，M.S. in Organic Chemistry

Department of Chemistry, Xiamen University, Xiamen, Fujian, China

July. 1995，B.S. in Organic Chemistry

Department of Chemistry, Xiamen University, Xiamen, Fujian, China

Dec. 2018-current，Professor

The Institute of Biopharmaceutical and Health Engineering (iBHE), SIGS, Tsinghua University

Dec. 2007-Nov. 2018，Associate Professor

Life Science and Health Division, The Graduate School at Shenzhen, Tsinghua University

Nov. 2005-Nov. 2007，Assistant Professor

Life Science and Health Division, The Graduate School at Shenzhen, Tsinghua University

Sep. 2004-Sep. 2005，Postdoctoral Fellow, Research Associate

Department of Chemistry, Northwestern University, USA

Director of Open Fiesta, Tsinghua Univ.

Member of the Committee of the Office of the State Key Laboratory of Chemical Oncogenomics

Member of the Teaching Committee of SIGS

Editorial Advisory Board member for ACS Applied Materials & Interfaces and Peptide & Protein Letters

 Chemical Biology

 Bootcamp: Fundamental Biology

My current research direction is chemical biology. I focus on (1) design new molecular structures and develop new synthetic methods for fluorescent functional molecules and materials, (2) develop analysis, imaging and artificial regulation for biological important targets and life processes for early diagnosis and treatment of diseases.

My projects have been funded by National Natural Science Foundation of China, Ministry of Education of China, and Shenzhen Municipal Government. I also participated actively in some major projects funded by Ministry of Science and Technology of China, including 863 Program, 973 Program, and National Science and Technology Major Project.

1.Jin, Y. Y.; Du, N.; Huang, Y. F.; Shen, W. X.; Tan, Y.; Chen, Y. Z.; Dou, W. T.; He, X. P.; Yang, Z. J.; Xu, N. H.; Tan, C. Y., Fluorescence Analysis of Circulating Exosomes for Breast Cancer Diagnosis Using a Sensor Array and Deep Learning. ACS Sensors 2022,7 (5), 1524-1532.

2.Zhang, P.; Tan, C., Cross-Reactive Fluorescent Sensor Array for Discrimination of Amyloid Beta Aggregates. Analytical Chemistry 2022,94 (14), 5469-5473.

3.Li, J.; Du, N.; Tan, Y.; Hsu, H.-Y.; Tan, C.; Jiang, Y., Conjugated Polymer Nanoparticles Based on Copper Coordination for Real-Time Monitoring of pH-Responsive Drug Delivery. ACS Applied Bio Materials 2021,4 (3), 2583-2590.

4.Li, J.; An, Z.; Sun, J.; Tan, C.; Gao, D.; Tan, Y.; Jiang, Y. Highly Selective Oxidation of Organic Sulfides by a Conjugated Polymer as the Photosensitizer for Singlet Oxygen Generation, ACS Appl. Mater. Interface, 2020, 12, 35475-35481.

5.Shen, Y.; Huang, Y.; Zhang, P.; Guo, B.; Jiang, H.; Tan, C.; Jiang, Y. Fluorescence Sensor Array for Discrimination of Urine Proteins and Differentiation Diagnosis of Urinary System Diseases, ACS Appl. Bio. Mater., 2020, 3, 5639-5643.

6.Pang, X. L.; Tan, Y.; Tan, C. Y.; Li, W. L.; Du, N.; Lu, Y. P.; Jiang, Y. Y., One-Step Construction of Fluorenone-Based Donor-Acceptor-Type Conjugated Polymers via Direct Arylation Polymerization for Cell-Imaging Applications. ACS Appl. Mater. Interfaces 2019,11, 28246-28253.

7.Li, S. F.; Gao, D.; Song, C.; Tan, C. Y.; Jiang, Y. Y., Isotope Labeling Strategies for Acylcarnitines Profile in Biological Samples by Liquid Chromatography-Mass Spectrometry. Anal. Chem. 2019,91, 1701-1705.

8.Chen, Y.; Tan, Y.; Tan, C.; Lu, Y.; Chen, Y.; Jiang, Y., Naphthalimide-containing conjugated polyelectrolytes with different chain configurations. Org Biomol Chem 2019,17, 2635-2639.

9.Li, A.; Tan, C.; Yuan, T.; Liang, J.; Gao, D.; Tan, Y.; Jiang, Y., Efficient photocatalytic oxidation sensitized by conjugated polymers in a batch reaction and microreactors under visible light. J. Mater. Chem. A 2018,6, 15927-15932.

10.Zhang, M. L.; Wu, P.; Dou, W. T.; Han, H. H.; He, X. P.; Tan, C. Y.; Jiang, Y. Y., Conjugated polyelectrolytes with galactose-containing side chains for targeted hepatoma cell imaging. Chem. Commun. 2017,53, 5625-5628.

11.Cai, K.; Tan, Y.; Tan, C. Y.; Wu, J. T.; Wu, P.; Liang, J. M.; Liu, S. W.; Zhang, B. B.; Jiang, Y. Y., An iminodiacetate-modified conjugated polyelectrolyte for fluorescent labeling of histidine-tagged proteins. Chem.Commun. 2017,53, 4191-4194.

12.Wu, P.; Xu, N. H.; Tan, C. Y.; Liu, L.; Tan, Y.; Chen, Z. F.; Jiang, Y. Y., Light-Induced Translocation of a Conjugated Polyelectrolyte in Cells: From Fluorescent Probe to Anticancer Agent. ACS Appl. Mater. Interfaces 2017,9, 10512-10518.

13.Dou, W.; Zhang, Y.; Lv, Y.; Wu, J.; Zang, Y.; Tan, C.; Li, J.; Chen, G.; He, X., Interlocked supramolecular glycoconjugated polymers for receptor-targeting theranostics. Chem. Commun. 2016,52, 3821-3824.

14.Dou, W.; Lv, Y.; Tan, C.; Chen, G.; He, X., Irreversible destruction of amyloid fibril plaques by conjugated polymer based fluorogenic nanogrenades. J. Mater. Chem. B 2016,4, 4502-4506. Featured article.

15.Liu, Y.; Wu, P.; Jiang, J.; Wu, J.; Chen, Y.; Tan, Y.; Tan, C.; Jiang, Y., Conjugated polyelectrolyte nanoparticles for apoptotic cell imaging. ACS Appl. Mater. Interfaces 2016,8, 21984-21989.

Outstanding Teachers in southern Guangdong in 2021

Tsinghua University Teaching Excellence Award in 2019

Chemical Biology ranked top 5% in the Teaching Evaluation of the Fall term in 2019

Excellent Master thesis advisor of Tsinghua University