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Biography
Education
2009.10-2013.10,University of Cambridge, Chemistry, PhD
2005.07-2009.07, Sun Yat-sen University, Polymer Materials and Engineering, BEng
Professional Experience
2020.08-now, Tsinghua University, Shenzhen International Graduate School, Associate Professor
2017.09-2020.08, Tsinghua-Berkeley Shenzhen Institute, Assistant Professor
2013.11-2017.08, University of Oxford, Postdoctoral Researcher
Additional Positions
Opening
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Current Courses
Precision Diagnosis Platform Design and Therapeutics Application,SIGS
Introduction to Mechanobiology, SIGS
Advances in Regenerative Medicine, SIGS
Medical Science Research, SIGS
Master’s & Ph.D. Advising
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Research Interests
Synthetic organoid technology for drug discovery, development and regenerative medicine,
Biomanufacturing technology and equipment R&D
Computational Biology
Projects
Research Output
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Selected Publications
[1] Ma, Shaohua*; Wang, Wanlong; Zhou, Jiaqi; Liao, Shangfeng; Hai, Cheng; Hou, Yibo; Zhou, Zhichun; Wang, Zitian; Su, Yingshi; Zhu, Yu; Dai, Xiaoyong; Zhao, Yuan; Liao, Sha; Cai, Yongde*; Xu, Xun*; Lamination-based Organoid Spatially Resolved Transcriptomics (LOSRT) Technique for Primary Lung and Liver Organoid Characterization, Proc. Natl. Acad. Sci., 2024, 121, e2408939121.
[2] Yang, Haowei; Li, Jiawei; Zheng, Yichao; Cao, Yuanxiong; Zhu, Yu; Sang, Gan; Galan, Edgar A; Ruan, Chuqian; Ma, Wilson M.J.; Dai, Xiaoyong; Cai, Yongde*; Ma, Shaohua*; Ultra-small tissue compatible organoid printer for rapid and controllable modeling of respiratory organoids, Device (Cell Press), 2024, 2: 100420.
[3] Zheng, Yichao; Han, Fei; Wu, Zhengyu; Wang, Bingjie; Chen, Xingchi; Boulouis, Caroline; Jiang, Yuebin; Ho, Amanda; He, Dan; Sia, Wan Rong; Mak, Jeffrey Y.W.; Fairlie, David P.; Wang, Lin-Fa; Sandberg, Johan K.; Lobie, Peter E.; Ma, Shaohua*; Leeansyah, Edwin*; MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis, Science Advances, 2024, 10: eadn6331.
[4] Zheng, Yichao; Tian, Qinyong; Yang, Haowei; Cai, Yongde; Zhang, Jiaxin; Wu, Yifen; Zhu, Shuo; Qiu, Zuocheng; Lin, Yimin; Hong, Jiangquan; Zhang, Yi; Dockrell, David; Ma, Shaohua*; Identification of nicotinic acetylcholine receptor for N-acetylcysteine to rescue nicotine induced injury using beating cilia in primary tissue derived airway organoids, Advanced Science, 2024, 2407054.
[5] Zhou, Jiaqi; Huang, Yi-chun; Wang, Wanlong; Li, Jiawei; Hou, Yibo; Yi, Ziqi; Yang, Haowei; Hu, Keer; Zhu, Yu; Wang, Zitian; Ma, Shaohua*; Chronotoxici-plate containing droplet engineered rhythmic liver organoids for drug toxicity evaluation, Advanced Science, 2024, 11: 2305925.
[6] Feng, Yilin; Fan, Jiaqi; Cheng, Yifan; Dai, Qionghai; Ma, Shaohua*; Stress regulates Alzheimer's disease progression via selective enrichment of CD8+ T cells, Cell Reports, 2023, 42(10): 113313.
[7] Tang, Xiaowei; Wang, Zitian; Khutsishvili, David; Cheng, Yifan; Wang, Jiaqi; Tang, Jiyuan; Ma, Shaohua*; Volumetric compression by heterogeneous scaffold embedding promotes cerebral organoid maturation and does not impede growth, Cell Systems, 2023, 14(10): 872-882.e3.
[8] Cao, Yuanxiong; Tan, Jiayi; Zhao, Haoran; Deng, Ting; Hu, Yunxia; Zeng, Junhong; Li, Jiawei; Cheng, Yifan; Tang, Jiyuan; Hu, Zhiwei; Hu, Keer; Xu, Bing; Wang, Zitian; Wu, Yaojiong; Lobie, Peter E; Ma, Shaohua*; Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration, Nature Communications, 2022, 13: 7463.
[9] Fan, Jiaqi; Feng, Yilin; Cheng, Yifan; Wang, Zitian; Zhao, Haoran; Galan, Edgar A.; Liao, Quanxing; Cui, Shuzhong; Zhang, Weijie; Ma, Shaohua*; Multiplex gene quantification as digital markers for extremely rapid evaluation of chemo-drug sensitivity, Patterns, 2021, 2: 100360.
[10] Jiang, Shengwei; Zhao, Haoran; Zhang, Weijie; Wang, Jiaqi; Liu, Yuhong; Cao, Yuanxiong; Zheng, Honghui; Hu, Zhiwei; Wang, Shubin; Zhu, Yu; Wang, Wei; Cui, Shuzhong; Lobie, Peter E.; Huang, Laiqiang*; Ma, Shaohua*; An automated organoid platform with inter-organoid homogeneity and inter-patient heterogeneity, Cell Reports Medicine, 2020, 1: 100161.
Books
Patents
Others
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Awards and Honors